Figure 7

Distal skin temperature. Changes in distal skin temperature (mean temperature of the forearm, back of the hand, dorsal side of the foot, and thigh corrected for body surface area; mean ± standard error) in summer D (●; n = 7), summer non-D (○; n = 8), winter D (■; n = 7), and winter non-D (□; n = 8) groups. ^aP < 0.05 compared with summer D (●) and winter D (■), and ^bP < 0.05 compared with summer non-D (○) and winter non-D (□). In a post hoc test, the mean distal skin temperature in both haplotype groups was significantly lower in winter than in summer at 0 and 10 minutes ( P < 0.05), but no differences were seen after that