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Table 1 Age-adjusted mean values and proportions by alkaline phosphatase levels

From: Association between alkaline phosphatase and hypertension in a rural Japanese population: The Nagasaki Islands study

 

ALP quartiles

 

Q1 (low)

Q2

Q3

Q4 (high)

P value

Men

  Median values for serum ALP (U/l)

172

209

250

318

 

  Number at risk

205

215

207

208

 

  Age (years)

63.9 ± 10.0

63.2 ± 11.5

65.3 ± 10.2

65.7 ± 10.2

 

  Systolic blood pressure (mmHg)

140

142

143

141

0.504

  Diastolic blood pressure (mmHg)

84

85

86

85

0.390

  Antihypertensive medication use (%)

27

22

25

26

0.735

  Thyroid disease (%)

0.0

0.5

1.0

0.0

0.300

  Body mass index (kg/m2)

23.7

23.8

23.6

23.3

0.337

  Current drinker (%)

62

53

46

45

0.002

  Current smoker (%)

20

23

27

29

0.105

  Serum triglycerides (mg/dl)

128

138

153

142

0.044

  Diabetes (%)

8

7

11

12

0.267

  Serum aspartate aminotransferase (AST) (IU/l)

24

25

25

26

0.061

  Serum γ-glutamyltranspeptidase (γ-GTP ) (IU/l)

36

41

51

60

<0.001

  Serum creatinine, (mg/dl)

0.90

0.93

0.92

0.91

0.562

  Glomerular filtration rate (ml/minute/1.73 m2)

70.3

68.4

68.5

70.7

0.411

Women

  Median values for serum ALP (U/l)

170

220

263

337

 

  Number at risk

465

458

467

456

 

  Age (years)

56.4 ± 12.8

63.7 ± 10.8

64.3 ± 9.6

65.8 ± 9.2

 

  Systolic blood pressure (mmHg)

137

140

141

142

<0.001

  Diastolic blood pressure (mmHg)

80

83

84

84

<0.001

  Antihypertensive medication use (%)

26

25

24

31

0.029

  Thyroid disease (%)

0.4

0.7

1.3

0.9

0.534

  Body mass index (kg/m2)

22.6

22.9

23.2

23.1

0.083

  Current drinker (%)

13.3

13.4

10.2

11.1

0.338

  Current smoker (%)

3.6

3.3

4.7

4.5

0.682

  Serum triglycerides (mg/dl)

113

118

127

133

<0.001

  Diabetes (%)

5.8

5.4

5.6

7.1

0.689

  Serum aspartate aminotransferase (AST) (IU/l)

21.4

21.9

22.0

23.1

0.011

  Serum γ-glutamyltranspeptidase (γ-GTP)IU/l)

20

24

25

31

<0.001

  Serum creatinine, (mg/dl)

0.724

0.715

0.716

0.724

0.740

  Glomerular filtration rate (ml/minute/1.73 m2)

66.7

67.7

67.7

66.5

0.574

  1. Age presented as mean ± standard deviation. Serum alkaline phosphatase (ALP) levels for quartiles were <194 U/l, 194 to 228 U/l, 229 to 275 U/l, and >275 U/l for men and <199 U/l, 199 to 240 U/l, 241 to 290 U/l, and >290 U/l for women.
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Journal of Physiological Anthropology

ISSN: 1880-6805

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