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Table 1 Clinical characteristics of study subjects by Mt5178 C/A genotype

From: Difference in effects of cigarette smoking or alcohol consumption on serum non-high-density lipoprotein cholesterol levels is related to mitochondrial DNA 5178 C/A polymorphism in middle-aged Japanese men: a cross-sectional study

  Mt5178C Mt5178A P value
  N = 239 N = 155  
Age (years) 54.3 ± 7.8 53.2 ± 7.8 0.171
Body mass index (kg/m2) 23.3 ± 2.8 23.5 ± 2.6 0.461
Serum total cholesterol (mg/dl) 203.5 ± 34.3 202.1 ± 31.8 0.672
Serum HDL cholesterol (mg/dl) 54.6 ± 13.6 56.3 ± 16.2 0.269
Serum non-HDL cholesterol (mg/dl) 148.9 ± 36.3 145.8 ± 34.6 0.395
Serum LDL cholesterol (mg/dl) 121.6 ± 34.8 117.9 ± 30.5 0.281
Serum triglyceride (mg/dl) 136.7 ± 91.1 139.5 ± 90.8 0.766
Systolic blood pressure (mmHg) 125.8 ± 15.9 125.7 ± 14.1 0.940
Diastolic blood pressure (mmHg) 74.0 ± 10.7 73.8 ± 9.1 0.823
Fasting plasma glucose (mg/dl) 97.2 ± 9.4 97.6 ± 9.7 0.672
Smoking status (never- or ex-/1-20 cigarettes per day/>20 cigarettes per day) (%) 59.4/29.7/10.9 59.4/25.8/14.8 0.429
Alcohol consumption (daily/occasionally/non- or ex-) (%) 46.4/35.2/18.4 47.7/38.7/13.6 0.426
Coffee consumption (≤1 cup per day/2-3 cups per day/≥4 cups per day) (%) 61.1/29.7/9.2 55.5/32.9/11.6 0.510
Antihypertensive (%) 18.8 12.9 0.122
  1. Age, body mass index, serum total cholesterol levels, serum HDL cholesterol levels, serum non-HDL cholesterol levels, serum LDL cholesterol levels, serum triglyceride levels, systolic blood pressure, diastolic blood pressure and fasting plasma glucose levels are given as means ± SD. For smoking status, alcohol consumption, coffee consumption and antihypertensive use, P values were calculated by chi-squared test. All P values depict significance of differences between mitochondrial DNA 5178 cytosine (Mt5178C) and mitochondrial DNA 5178 adenosine (Mt5178A). HDL, high-density lipoprotein; LDL, low-density lipoprotein.