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Table 2 Serum non-HDL cholesterol levels classified by smoking status and Mt5178 C/A genotype

From: Difference in effects of cigarette smoking or alcohol consumption on serum non-high-density lipoprotein cholesterol levels is related to mitochondrial DNA 5178 C/A polymorphism in middle-aged Japanese men: a cross-sectional study

 

Smoking status

P for trend

 

Never- or ex-smokers

1-20 cigarettes smoked per day

>20 cigarettes smoked per day

 

Mt5178C

N = 142

N = 70

N = 27

 

non-HDL cholesterol

149.2 ± 3.0

144.7 ± 4.3

158.6 ± 7.0

P = 0.557

non-HDL cholesterol†

148.8 ± 3.0

145.4 ± 4.3

160.5 ± 7.0

P = 0.333

non-HDL cholesterol‡

151.8 ± 4.6

146.8 ± 5.2

162.3 ± 7.7

P = 0.500

Mt5178A

N = 92

N = 40

N = 23

 

non-HDL cholesterol

139.9 ± 3.5

145.8 ± 5.3

169.3 ± 6.9**,§

P < 0.001

non-HDL cholesterol†

139.0 ± 3.4

149.4 ± 5.2

166.7 ± 6.7*

P < 0.001

non-HDL cholesterol‡

141.2 ± 5.4

150.1 ± 6.1

168.0 ± 8.1*

P < 0.001

  1. †non-HDL cholesterol levels are given as least-square mean ± SE adjusted for age and body mass index; ‡non-HDL cholesterol levels are given as least-square mean ± SE adjusted for age, body mass index, alcohol consumption, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was applied. *P < 0.005 vs never- or ex-smokers, **P < 0.001 vs never- or ex-smokers, §P < 0.001 vs current smokers who smoked 1 to 20 cigarettes per day. HDL, high-density lipoprotein; Mt5178C, mitochondrial DNA 5178 cytosine; Mt5178A, mitochondrial DNA 5178 adenosine.
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Journal of Physiological Anthropology

ISSN: 1880-6805

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