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Table 4 Serum non-HDL cholesterol levels classified by drinking status and Mt5178 C/A genotype

From: Difference in effects of cigarette smoking or alcohol consumption on serum non-high-density lipoprotein cholesterol levels is related to mitochondrial DNA 5178 C/A polymorphism in middle-aged Japanese men: a cross-sectional study

 

Drinking status

P for trend

 

Non- or ex-drinkers

Occasional drinkers

Daily drinkers

 

Mt5178C

N = 44

N = 84

N = 111

 

non-HDL cholesterol

159.8 ± 5.4

146.2 ± 3.9

146.7 ± 3.4

P = 0.088

non-HDL cholesterol†

161.8 ± 5.4

145.7 ± 3.9*

146.3 ± 3.4*

P = 0.043

non-HDL cholesterol‡

164.5 ± 6.7

148.0 ± 5.5*

148.4 ± 4.6*

P = 0.040

Mt5178A

N = 21

N = 60

N = 74

 

non-HDL cholesterol

151.2 ± 7.6

147.9 ± 4.5

142.6 ± 4.0

P = 0.245

non-HDL cholesterol†

153.7 ± 7.4

147.6 ± 4.3

142.1 ± 3.9

P = 0.140

non-HDL cholesterol‡

159.7 ± 8.3

152.3 ± 5.7

147.3 ± 5.3

P = 0.114

  1. †non-HDL cholesterol levels are given as least-square mean ± SE adjusted for age and body mass index; ‡non-HDL cholesterol levels are given as least-square mean ± SE adjusted for age, body mass index, cigarette smoking, coffee consumption and antihypertensive medication use. Bonferroni correction for multiple comparisons was applied. *P < 0.05 vs non- or ex-drinkers. HDL, high-density lipoprotein; Mt5178C, mitochondrial DNA 5178 cytosine; Mt5178A, mitochondrial DNA 5178 adenosine.