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Table 5 Odds ratios and 95% confidence intervals for high levels of serum non-HDL cholesterol by Mt5178 C/A genotype and drinking status

From: Difference in effects of cigarette smoking or alcohol consumption on serum non-high-density lipoprotein cholesterol levels is related to mitochondrial DNA 5178 C/A polymorphism in middle-aged Japanese men: a cross-sectional study

Genotype and alcohol consumption Frequency OR (95% CI) Adjusted OR(95% CI) Adjusted OR(95% CI)
Normal levels of serum non-HDL cholesterol High levels of serum non-HDL cholesterol
  non-HDL cholesterol <160 mg/dl non-HDL cholesterol ≥160 mg/dl    
Mt5178C      
Non- or ex-drinkers 22 (50.0) 22 (50.0) 1 (reference) 1 (reference) 1 (reference)
Occasional drinkers 55 (65.5) 29 (34.5) 0.527 (0.251-1.108) 0.430 (0.194-0.953)* 0.439 (0.190-1.016)
Daily drinkers 80 (72.1) 31 (27.9) 0.388 (0.188-0.798)* 0.308 (0.142-0.665)** 0.312 (0.139-0.698)**
    P for trend = 0.012 P for trend = 0.005 P for trend = 0.005
Mt5178A      
Non- or ex-drinkers 17 (81.0) 4 (19.0) 1 (reference) 1 (reference) 1 (reference)
Occasional drinkers 38 (63.3) 22 (36.7) 2.461 (0.734-8.244) 2.491 (0.720-8.619) 2.499 (0.649-9.618)
Daily drinkers 48 (64.9) 26 (35.1) 2.302 (0.701-7.561) 2.022 (0.595-6.875) 2.114 (0.583-7.665)
    P for trend = 0.310 P for trend = 0.385 P for trend = 0.348
  non-HDL cholesterol <190 mg/dl non-HDL cholesterol ≥190 mg/dl    
Mt5178C      
Non- or ex-drinkers 36 (81.5) 8 (18.2) 1 (reference) 1 (reference) 1 (reference)
Occasional drinkers 74 (88.1) 10 (11.9) 0.608 (0.221-1.672) 0.627 (0.221-1.780) 0.858 (0.279-2.640)
Daily drinkers 100 (90.1) 11 (9.9) 0.495 (0.184-1.328) 0.408 (0.146-1.139) 0.330 (0.108-1.003)
    P for trend = 0.181 P for trend = 0.140 P for trend = 0.123
Mt5178A      
Non- or ex-drinkers 19 (90.5) 2 (9.5) 1 (reference) 1 (reference) 1 (reference)
Occasional drinkers 54 (90.0) 6 (10.0) 1.056 (0.196-5.684) 1.014 (0.176-5.853) 0.938 (0.154-5.714)
Daily drinkers 64 (86.5) 10 (13.5) 1.484 (0.299-7.368) 1.190 (0.230-6.156) 1.325 (0.219-7.996)
    P for trend = 0.513 P for trend = 0.605 P for trend = 0.560
  1. OR adjusted for age and body mass index. OR adjusted for age, body mass index, cigarette smoking, coffee consumption and antihypertensive medication. *P < 0.05, **P < 0.005. CI, confidence interval; HDL, high-density lipoprotein; Mt5178C, mitochondrial DNA 5178 cytosine; Mt5178A, mitochondrial DNA 5178 adenosine; OR, odds ratio.