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Table 2 The comparison of specific pathogen bound by HLA-DRB1 molecules between Group A and Group B

From: A human-specific allelic group of the MHC DRB1 gene in primates

Source organism ID

Source organism name

HLA-DRB1 molecule

 

520

Bordetella pertussis

HLA-DRB1*11:01

Group A

1309

Streptococcus mutans

HLA-DRB1*08:02

6956

Dermatophagoides pteronyssinus

HLA-DRB1*11:01

10408

Hepatitis B virus subtype adw2

HLA-DRB1*12:01

10580

Human papillomavirus type 11

HLA-DRB1*03:01

11234

Measles virus

HLA-DRB1*11:01, 11:03

206203

Influenza B virus [B/Hong Kong/330/2001]

HLA-DRB1*14:01

385630

Influenza A virus [A/Bangkok/1/1979(H3N2)]

HLA-DRB1*12:01

387161

Influenza A virus [A/Japan/305/1957(H2N2)]

HLA-DRB1*11:01, 11:02, 11:03, 11:04

10000974

Streptococcus mutans GS-5

HLA-DRB1*08:02

210

Helicobacter pylori

HLA-DRB1*04:01, 15:01

Group B

236

Brucella ovis

HLA-DRB1*04:01, 04:07

562

Escherichia coli

HLA-DRB1*04:01, 07:01, 15:01

1313

Streptococcus pneumoniae

HLA-DRB1*15:01

1358

Lactococcus lactis

HLA-DRB1*04:01, 04:07

1423

Bacillus subtilis

HLA-DRB1*15:01

1764

Mycobacterium avium

HLA-DRB1*15:01

4479

Poaceae

HLA-DRB1*15:01

10254

Vaccinia virus WR

HLA-DRB1*04:01

10309

Herpes simplex virus (type 1/strain SC16)

HLA-DRB1*04:01, 15:01

10957

Human rotavirus strain P

HLA-DRB1*04:01, 04:04, 15:01

11309

Unidentified influenza virus

HLA-DRB1*04:01

11679

HIV type 1 (CLONE 12)

HLA-DRB1*09:01

11694

HIV virus type 1 (JH3 ISOLATE)

HLA-DRB1*09:01, 15:01

12721

HIV

HLA-DRB1*01:03

130763

Influenza A virus [A/Hong Kong/156/97(H5N1)]

HLA-DRB1*09:01

197911

Influenza virus A

HLA-DRB1*04:01, 04:05

211044

Influenza A virus [A/Puerto Rico/8/1934(H1N1)]

HLA-DRB1*04:01, 04:05

243160

Burkholderia mallei ATCC 23344

HLA-DRB1*04:01

351073

Mammalian orthoreovirus

HLA-DRB1*04:01, 15:01

 

381512

Influenza A virus [A/New Caledonia/20/1999(H1N1)]

HLA-DRB1*04:01

381513

Influenza A virus [A/Panama/2007/1999(H3N2)]

HLA-DRB1*04:01

382781

Influenza A virus [A/Singapore/1/1957(H2N2)]

HLA-DRB1*09:01

641501

Influenza A virus [A/California/04/2009(H1N1)]

HLA-DRB1*04:01

746128

Aspergillus fumigatus

HLA-DRB1*15:01, 15:02

768646

Influenza A virus [A/chicken/Uchal/8293/2006(H9N2)]

HLA-DRB1*09:01

768647

Influenza A virus [A/chicken/Uchal/8286/2006(H9N2)]

HLA-DRB1*09:01

991335

Influenza A virus [A/swine/Hong Kong/71/2009(H1N1)]

HLA-DRB1*09:01

  1. The dataset of source organism bound to HLA-DRB1 molecules was acquired from the MHC binding assay in the IEDB database.