|
Variable
|
Mean ± SD
| |
|---|
|
Subjects homozygous for all four SNPsa
|
Subjects not homozygous for all four SNPs
|
P
|
|---|
|
(n = 70)
|
(n = 338)
|
|---|
|
SBP (mmHg)
|
137.40 ± 19.83
|
139.83 ± 22.23
|
0.398
|
|
DBP (mmHg)
|
81.55 ± 10.51
|
80.98 ± 10.78
|
0.688
|
|
Pulse rate (bpm)
|
74.48 ± 12.60
|
73.98 ± 13.10
|
0.768
|
|
WC (cm)
|
90.94 ± 12.50
|
91.01 ± 11.51
|
0.966
|
|
HC (cm)
|
101.20 ± 11.09
|
102.13 ± 9.91
|
0.484
|
|
WHR
|
0.90 ± 0.08
|
0.89 ± 0.08
|
0.457
|
|
Height (cm)
|
161.11 ± 8.54
|
159.81 ± 9.39
|
0.283
|
|
Weight (kg)
|
70.38 ± 16.34
|
69.59 ± 14.63
|
0.686
|
|
BMI (kg/m2)
|
27.04 ± 5.57
|
27.20 ± 5.00
|
0.813
|
|
TBFb (%)
|
31.92 ± 6.53
|
33.59 ± 6.98
|
0.131
|
|
SFb (%)
|
25.25 ± 7.84
|
27.60 ± 8.20
|
0.045
|
|
VFLb (%)
|
12.64 ± 6.87
|
12.19 ± 6.23
|
0.672
|
|
RM (kcal)
|
1,491.96 ± 282.82
|
1,448.95 ± 258.76
|
0.214
|
|
SMb (%)
|
25.78 ± 3.82
|
24.91 ± 4.08
|
0.084
|
|
Leptinb (ng/mL)
|
21.22 ± 27.96
|
30.50 ± 37.77
|
0.015
|
- All values by Student’s t-test, significant at P < 0.05 and indicated in bold font.
- aSubjects with homozygous mutated genotypes for all four SNPs: GG for LEP A19G, AA for LEP G2548A, RR for both LEPR K109R and LEPR Q223R.
- bValues were log transformed before analysis.
