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Table 3 The relationship between genotype combinations with blood pressures, anthropometric variables, and plasma leptin levels

From: Leptin and leptin receptor gene polymorphisms and their association with plasma leptin levels and obesity in a multi-ethnic Malaysian suburban population

Variable Mean ± SD  
Subjects homozygous for all four SNPsa Subjects not homozygous for all four SNPs P
(n = 70) (n = 338)
SBP (mmHg) 137.40 ± 19.83 139.83 ± 22.23 0.398
DBP (mmHg) 81.55 ± 10.51 80.98 ± 10.78 0.688
Pulse rate (bpm) 74.48 ± 12.60 73.98 ± 13.10 0.768
WC (cm) 90.94 ± 12.50 91.01 ± 11.51 0.966
HC (cm) 101.20 ± 11.09 102.13 ± 9.91 0.484
WHR 0.90 ± 0.08 0.89 ± 0.08 0.457
Height (cm) 161.11 ± 8.54 159.81 ± 9.39 0.283
Weight (kg) 70.38 ± 16.34 69.59 ± 14.63 0.686
BMI (kg/m2) 27.04 ± 5.57 27.20 ± 5.00 0.813
TBFb (%) 31.92 ± 6.53 33.59 ± 6.98 0.131
SFb (%) 25.25 ± 7.84 27.60 ± 8.20 0.045
VFLb (%) 12.64 ± 6.87 12.19 ± 6.23 0.672
RM (kcal) 1,491.96 ± 282.82 1,448.95 ± 258.76 0.214
SMb (%) 25.78 ± 3.82 24.91 ± 4.08 0.084
Leptinb (ng/mL) 21.22 ± 27.96 30.50 ± 37.77 0.015
  1. All values by Student’s t-test, significant at P < 0.05 and indicated in bold font.
  2. aSubjects with homozygous mutated genotypes for all four SNPs: GG for LEP A19G, AA for LEP G2548A, RR for both LEPR K109R and LEPR Q223R.
  3. bValues were log transformed before analysis.