Skip to main content

Table 2 Erythrocytic parameters by coffee consumption status and Mt5178 C/A genotype

From: Longevity-associated mitochondrial DNA 5178 C/A polymorphism modulates the effects of coffee consumption on erythrocytic parameters in Japanese men: an exploratory cross-sectional analysis

 

Coffee consumption

P for trend

 

<1 cup per day

1 to 3 cups per day

≥4 cups per day

 

Mt5178C

N = 119

N = 123

N = 24

 

Red blood cell count (104/μL)

480 ± 3

481 ± 3

468 ± 8

0.349

Red blood cell count (104/μL)a

484 ± 3

480 ± 3

463 ± 7*

0.022

Hematocrit (%)

43.9 ± 0.3

43.8 ± 0.3

43.1 ± 0.6

0.426

Hematocrit (%)a

43.9 ± 0.3

43.5 ± 0.3

42.6 ± 0.6

0.059

Hemoglobin (g/dL)

15.0 ± 0.1

14.9 ± 0.1

14.8 ± 0.2

0.329

Hemoglobin (g/dL)a

15.0 ± 0.1

14.8 ± 0.1

14.6 ± 0.2

0.035

Mean corpuscular volume (fl)

91.4 ± 0.4

91.2 ± 0.4

92.2 ± 0.9

0.681

Mean corpuscular volume (fl)a

90.8 ± 0.4

90.9 ± 0.4

92.1 ± 0.8

0.275

Mt5178A

N = 62

N = 87

N = 21

 

Red blood cell count (104/μL)

490 ± 5

485 ± 4

487 ± 9

0.615

Red blood cell count (104/μL)a

491 ± 5

483 ± 5

487 ± 9

0.485

Hematocrit (%)

44.2 ± 0.4

44.2 ± 0.3

44.6 ± 0.6

0.668

Hematocrit (%)a

44.4 ± 0.4

44.1 ± 0.3

44.4 ± 0.6

0.889

Hemoglobin (g/dL)

15.1 ± 0.1

15.1 ± 0.1

15.2 ± 0.2

0.758

Hemoglobin (g/dL)a

15.2 ± 0.1

15.0 ± 0.1

15.1 ± 0.2

0.711

Mean corpuscular volume (fl)

90.6 ± 0.6

91.5 ± 0.5

91.7 ± 1.0

0.247

Mean corpuscular volume (fl)a

90.8 ± 0.6

91.5 ± 0.5

91.4 ± 0.9

0.451

  1. aMean ± standard error adjusted for age, body mass index, alcohol consumption, habitual smoking and green tea consumption. Bonferroni correction for multiple comparison was applied. *P <0.05 versus <1 cup of coffee per day.