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Table 3 Odds ratios and 95% confidence intervals for anemia (hemoglobin <14 g/dL) by Mt5178 C/A genotype and coffee consumption

From: Longevity-associated mitochondrial DNA 5178 C/A polymorphism modulates the effects of coffee consumption on erythrocytic parameters in Japanese men: an exploratory cross-sectional analysis

Genotype and coffee consumption Frequency (%) Odds ratio (95% confidence interval) Adjusted odds ratioa(95% confidence interval)
Normal hemoglobin level (hemoglobin ≥14 g/dL) Anemia (hemoglobin <14 g/dL)
Mt5178C     
<1 cup per day 99 (83.2) 20 (16.8) 1 (reference) 1 (reference)
1 to 3 cups per day 104 (84.6) 19 (15.4) 0.904 (0.456 to 1.795) 1.140 (0.527 to 2.467)
≥4 cups per day 17 (70.8) 7 (29.2) 2.038 (0.748 to 5.556) 3.771 (1.088 to 13.06)*
    P for trend = 0.386 P for trend = 0.078
Mt5178A     
<1 cup per day 51 (82.3) 11 (17.7) 1 (reference) 1 (reference)
1 to 3 cups per day 80 (92.0) 7 (8.0) 0.406 (0.148 to 1.115) 0.383 (0.118 to 1.249)
≥4 cups per day 20 (95.2) 1 (4.8) 0.232 (0.028 to 1.915) 0.301 (0.029 to 3.094)
    P for trend = 0.049 P for trend = 0.137
  1. aOdds ratio adjusted for age, body mass index, habitual alcohol consumption, habitual smoking and green tea consumption. *P <0.05.