Non-chronic kidney diseased | Chronic kidney diseasec | P | ||
---|---|---|---|---|
Normal renal functiona | Mild renal impairmentb | |||
Number at risk | 109 | 645 | 351 | |
Age, years | 67.7 ± 6.1 | 69.6 ± 6.5 | 72.2 ± 6.7 | |
Systolic blood pressure, mmHg | 143 | 143 | 145 | 0.344 |
Antihypertensive medication use, % | 31.5 | 34.3 | 40.6 | 0.083 |
Diabetes, % | 14.0 | 12.0 | 10.7 | 0.634 |
History of cardiovascular disease, % | 8.8 | 10.2 | 17.4 | 0.003 |
Body mass index, kg/m2 | 22.8 | 23.5 | 23.9 | 0.003 |
Current drinkers, % | 56 | 46.8 | 51.1 | 0.126 |
Current smokers, % | 29.1 | 21.6 | 15.2 | 0.004 |
Serum HDL cholesterol, mg/dL | 57 | 55 | 52 | 0.004 |
Serum triglycerides (TG), mg/dL | 116 | 112 | 135 | <0.001 |
Serum aspartate aminotransferase (AST), IU/L | 27 | 25 | 24 | 0.021 |
Serum γ-glutamyltraspeptidase (γGTP), IU/L | 44 | 37 | 46 | 0.046 |
Serum creatinine, mg/dL | 0.62 | 0.82 | 1.18 | <0.001 |
Glomerular filtration rate (GFR), mL/min/1.73 m2 | 99.6 | 72.4 | 49.8 | <0.001 |