Brain activation during processing of angry facial expressions in patients with alcohol dependency

Table 2 Talairach coordinates and t -scores of activated brain areas

Region	Side	X	Y	Z	Brodmann’s areas (BA)	t -value
Angry face-fixation comparison
The control group
Dorsolateral prefrontal cortex	Right	46	16	20	46	5.60
Culmen	Right	46	−46	−28		4.60
	Left	−44	−52	−18		3.40
Ventrolateral prefrontal cortex	Left	−58	22	20	45	4.17
	Left	−44	16	0		3.64
Lateral orbital frontal cortex	Left	−34	34	−2	47	3.72
Superior parietal lobule	Right	40	−56	50	7	4.05
Inferior temporal gyrus	Left	−52	−24	−18	20	3.98
Middle temporal gyrus	Left	−58	−66	24	39	3.66
	Right	46	6	−30	21	3.80
	Right	64	−52	−2	37	5.15
Thalamus	Left	−6	−30	16		3.76
Anterior temporal lobe	Left	−34	10	−32	38	3.64
	Left	−66	−40	6	22	3.34
The patient group
Superior frontal gyrus	Right	6	18	60	6	6.61
Inferior temporal gyrus	Left	−44	−2	−36	20	4.28
Middle frontal gyrus	Left	−34	0	54	6	4.26
Cingulate gyrus	Left	−20	−12	44	24	4.18
Postcentral gyrus	Right	66	−10	20	43	4.04
Superior temporal gyrus	Right	48	20	−22	38	3.78
Middle temporal gyrus	Right	50	−30	−8	21	8.18
Uncus/parahippocampal gyrus	Left	−24	−2	−26		3.53
Precuneus	Left	−8	−52	62	7	3.08
Contrasted brain activation areas
The patient group > the control group
Superior temporal gyrus	Right	62	−32	8	22	4.70
	Right	56	−2	−6	22	3.23
	Right	40	−30	8	41	3.20
Supplementary motor area	Right	4	−10	68	6	3.98
Superior temporal gyrus	Left	−56	−16	6	41	3.68
Medial prefrontal cortex	Left	−2	50	30	9	3.40
Thalamus	Right	6	−10	2		3.30
Postcentral gyrus	Right	64	−8	18	43	3.18
Dorsal anterior cingulate cortex	Left	−10	32	10	32	3.16
Cerebellar tonsil	Right	32	−56	−44		3.12
	Right	24	−32	−38		3.02
Cingulate gyrus	Right	8	22	32	32	2.93

Brain activation comparisons between the angry face and the fixation conditions in each group and contrasting effects between two groups (that is, the patient group versus control group) (uncorrected P < 0.001).

ISSN: 1880-6805