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Table 2 Carotid atherosclerosis in relation to hemoglobin A1c (HbA1c) levels

From: Association between hemoglobin A1c and carotid atherosclerosis in rural community-dwelling elderly Japanese men

 

HbA1c level quintiles

Q1 (low)

Q2

Q3

Q4

Q5 (high)

Total subjects

 No. at risk

190

205

258

246

251

 No. of cases (percentage)

57 (30.0)

64 (31.2)

67 (26.0)

71 (28.9)

83 (33.1)

 Age-adjusted odds ratio (OR)

1.24 (0.81 to 1.90)

1.28 (0.84 to 1.95)

1.00

1.13 (0.76 to 1.68)

1.42 (0.94 to 2.10)

 Multivariable OR

1.21 (0.78 to 1.88)

1.36 (0.88 to 2.11)

1.00

1.13 (0.82 to 2.01)

1.13 (0.74 to 1.71)

Low BMI

 No. at risk

103

102

127

98

90

 No. of cases (percentage)

35 (34.0)

35 (34.3)

25 (19.7)

27 (27.6)

21 (23.3)

 Age-adjusted OR

2.01 (1.08 to 3.73)

2.01 (1.07 to 3.75)

1.00

1.44 (0.76 to 2.72)

1.23 (0.63 to 2.40)

 Multivariable OR

1.78 (0.92 to 3.44)

2.05 (1.06 to 3.96)

1.00

1.55 (0.77 to 3.09)

1.26 (0.58 to 2.76)

High BMI

 No. at risk

87

103

131

148

161

 No. of cases (percentage)

22 (25.3)

29 (28.2)

42 (32.1)

44 (29.7)

62 (38.5)

 Age-adjusted OR

0.78 (0.42 to 1.45)

0.86 (0.49 to 1.53)

1.00

0.90 (0.54 to 1.51)

1.35 (0.83 to 2.22)

 Multivariable OR

0.66 (0.35 to 1.27)

0.94 (0.51 to 1.73)

1.00

0.91 (0.53 to 1.55)

1.26 (0.72 to 2.22)

  1. Multivariable: adjusted further for age, systolic blood pressure, antihypertensive medication use, body mass index, smoking, alcohol intake, taking medication for cardiovascular disease, use of glucose-lowering medication, lipid-lowering medication use, serum triglyceride (TG), serum HDL-cholesterol, serum aspartate aminotransferase (AST), and estimated glomerular filtration rate (GFR). Low body mass index (BMI) consists of BMI <23 kg/m2 and high BMI consists of BMI ≥23 kg/m2.