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Table 2 Carotid atherosclerosis in relation to hemoglobin A1c (HbA1c) levels

From: Association between hemoglobin A1c and carotid atherosclerosis in rural community-dwelling elderly Japanese men

  HbA1c level quintiles
Q1 (low) Q2 Q3 Q4 Q5 (high)
Total subjects
 No. at risk 190 205 258 246 251
 No. of cases (percentage) 57 (30.0) 64 (31.2) 67 (26.0) 71 (28.9) 83 (33.1)
 Age-adjusted odds ratio (OR) 1.24 (0.81 to 1.90) 1.28 (0.84 to 1.95) 1.00 1.13 (0.76 to 1.68) 1.42 (0.94 to 2.10)
 Multivariable OR 1.21 (0.78 to 1.88) 1.36 (0.88 to 2.11) 1.00 1.13 (0.82 to 2.01) 1.13 (0.74 to 1.71)
Low BMI
 No. at risk 103 102 127 98 90
 No. of cases (percentage) 35 (34.0) 35 (34.3) 25 (19.7) 27 (27.6) 21 (23.3)
 Age-adjusted OR 2.01 (1.08 to 3.73) 2.01 (1.07 to 3.75) 1.00 1.44 (0.76 to 2.72) 1.23 (0.63 to 2.40)
 Multivariable OR 1.78 (0.92 to 3.44) 2.05 (1.06 to 3.96) 1.00 1.55 (0.77 to 3.09) 1.26 (0.58 to 2.76)
High BMI
 No. at risk 87 103 131 148 161
 No. of cases (percentage) 22 (25.3) 29 (28.2) 42 (32.1) 44 (29.7) 62 (38.5)
 Age-adjusted OR 0.78 (0.42 to 1.45) 0.86 (0.49 to 1.53) 1.00 0.90 (0.54 to 1.51) 1.35 (0.83 to 2.22)
 Multivariable OR 0.66 (0.35 to 1.27) 0.94 (0.51 to 1.73) 1.00 0.91 (0.53 to 1.55) 1.26 (0.72 to 2.22)
  1. Multivariable: adjusted further for age, systolic blood pressure, antihypertensive medication use, body mass index, smoking, alcohol intake, taking medication for cardiovascular disease, use of glucose-lowering medication, lipid-lowering medication use, serum triglyceride (TG), serum HDL-cholesterol, serum aspartate aminotransferase (AST), and estimated glomerular filtration rate (GFR). Low body mass index (BMI) consists of BMI <23 kg/m2 and high BMI consists of BMI ≥23 kg/m2.