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Table 4 Carotid atherosclerosis in relation to hemoglobin A1c (HbA1c) levels in subjects not taking medication

From: Association between hemoglobin A1c and carotid atherosclerosis in rural community-dwelling elderly Japanese men

  HbA 1c level quintiles
Q1 (low) Q2 Q3 Q4 Q5 (high)
Total subject
 No. at risk 168 180 216 192 138
 No. of cases (percentage) 51 (30.4) 54 (30.0) 51 (23.6) 54 (28.1) 46 (33.3)
 Age-adjusted odds ratio (OR) 1.42 (0.89 to 2.26) 1.35 (0.85 to 2.13) 1.00 1.26 (0.80 to 1.98) 1.62 (1.00 to 2.63)
 Multivariable OR 1.36 (0.84 to 2.20) 1.44 (0.89 to 2.33) 1.00 1.30 (0.80 to 2.10) 1.58 (0.94 to 2.66)
Low body mass index (BMI)
 No. at risk 92 91 111 78 50
 No. of cases (percentage) 33 (35.9) 29 (31.9) 20 (18.0) 19 (24.4) 10 (20.0)
 Age-adjusted OR 2.40 (1.24 to 4.67) 2.04 (1.03 to 4.01) 1.00 1.42 (0.69 to 2.91) 1.13 (0.48 to 2.67)
 Multivariable OR 2.29 (1.12 to 4.66) 2.15 (1.05 to 4.39) 1.00 1.50 (0.67 to 3.33) 0.99 (0.39 to 2.53)
High BMI
 No. at risk 76 89 105 114 88
 No. of cases (percentage) 18 (23.7) 25 (28.1) 31 (29.5) 35 (30.7) 36 (40.9)
 Age-adjusted OR 0.80 (0.41 to 1.59) 0.93 (0.49 to 1.74) 1.00 1.07 (0.59 to 1.92) 1.66 (0.90 to 3.05)
 Multivariable OR 0.68 (0.33 to 1.41) 1.09 (0.55 to 2.16) 1.00 1.19 (0.64 to 2.21) 2.01 (1.04 to 3.90)
  1. Multivariable: adjusted further for age, systolic blood pressure, antihypertensive medication use, body mass index, smoking, alcohol intake, serum triglyceride (TG), serum HDL-cholesterol, serum aspartate aminotransferase (AST), and estimated glomerular filtration rate (GFR). Low BMI consists of BMI <23 kg/m2 and high BMI consists of BMI ≥23 kg/m2.