Fig. 3

Effect of the presence of light on brain responses of younger and older individuals performing an auditory two-back task. Statistical results (p < 0.001 uncorrected) overlaid over the mean structural image of all participants. Significant responses to light are displayed in yellow for younger individuals (Y), in red for older individuals (O), whereas group differences (Y > O) are in blue. Right panels a-l show activity estimates (arbitrary unit (a.u.) ± standard error of the mean) in each brain region. *Significantly activated, p < 0.05 corrected for multiple comparisons over small volumes of interest; # significant group differences, p < 0.05 corrected for multiple comparisons over small volumes of interest. Abbreviations: a LGN lateral geniculate nucleus, b LING lingual gyrus, c CALC calcarine sulcus, d MOG/SOG middle and superior occipital gyrus, e FPC frontopolar cortex, f THAL dorsomedian thalamus, g PULV thalamus pulvinar, h INSULA insula, i AMYG amygdala, j TEGM tegmentum, k CEREB cerebellum, l OPERC frontal operculum. Please refer to Table 2 of [113] for brain clusters coordinates. Reproduced with permission from [117]