| |
Sarcopenia defined by ASM/Ht2
|
Sarcopenia defined by ASM/Wt
|
|---|
|
Normal
|
Class 1
|
Class 2
|
*P value
|
Normal
|
Class 1
|
Class 2
|
*P value
|
|---|
|
Sarcopenia
|
Sarcopenia
|
One-way ANCOVA
|
Post hoc analysis
|
Sarcopenia
|
Sarcopenia
|
One-way ANCOVA
|
Post hoc analysis
|
|---|
|
Number
|
185 (67.8%)
|
76 (27.8%)
|
12 (4.4%)
|
–
|
–
|
168 (61.5%)
|
89 (32.6%)
|
16 (5.9%)
|
–
|
–
|
|
Age (years)
|
57 ± 10
|
64 ± 13
|
70 ± 14
|
–
|
–
|
57 ± 11
|
62 ± 12
|
69 ± 11
|
–
|
–
|
|
Height (cm)
|
169.5 ± 6.2
|
167.5 ± 5.9
|
164.4 ± 7.4
|
N.S.
| |
169.2 ± 6.5
|
168.1 ± 5.8
|
166.6 ± 6.7
|
N.S.
| |
|
Weight (kg)
|
66.0 ± 5.5
|
60.5 ± 6.3
|
53.4 ± 6.5
|
<0.001
|
a,b,c
|
63.5 ± 6.8
|
64.8 ± 6.1
|
63.1 ± 8.2
|
<0.01
| |
|
BMI (kg/m2)
|
23.0 ± 1.2
|
21.5 ± 1.5
|
19.5 ± 1.4
|
<0.001
|
a,b,c
|
22.1 ± 1.6
|
22.9 ± 1.3
|
22.7 ± 1.8
|
N.S.
| |
|
WC (cm)
|
82.9 ± 5.2
|
81.5 ± 5.8
|
75.1 ± 5.2
|
<0.001
|
a,b,c
|
80.2 ± 5.1
|
85.1 ± 4.4
|
84.9 ± 7.3
|
N.S.
| |
|
Percent body fat (%)
|
19.7 ± 3.7
|
20.8 ± 4.2
|
20.1 ± 4.0
|
–
|
–
|
18.1 ± 3.4
|
22.9 ± 2.0
|
24.4 ± 3.4
|
–
|
–
|
|
Handgrip strength (kg)
|
40.5 ± 7.0
|
34.9 ± 6.1
|
31.9 ± 6.5
|
<0.001
|
a,b
|
40.7 ± 6.9
|
35.5 ± 6.7
|
33.5 ± 6.1
|
<0.01
|
a,b
|
|
Whole-body BMD (g/cm2)
|
1.142 ± 0.109
|
1.078 ± 0.084
|
1.019 ± 0.113
|
<0.001
|
a,b
|
1.133 ± 0.104
|
1.097 ± 0.107
|
1.091 ± 0.135
|
N.S.
| |
|
Arm BMD (g/cm2)
|
0.799 ± 0.059
|
0.752 ± 0.049
|
0.713 ± 0.057
|
<0.001
|
a,b,c
|
0.793 ± 0.059
|
0.766 ± 0.061
|
0.755 ± 0.061
|
N.S.
| |
|
Lumbar spine BMD (g/cm2)
|
1.076 ± 0.190
|
1.012 ± 0.193
|
0.944 ± 0.223
|
<0.01
|
a,b
|
1.065 ± 0.181
|
1.027 ± 0.206
|
1.067 ± 0.261
|
N.S.
| |
|
Leg BMD (g/cm2)
|
1.246 ± 0.113
|
1.158 ± 0.088
|
1.068 ± 0.089
|
<0.001
|
a,b,c
|
1.234 ± 0.117
|
1.184 ± 0.103
|
1.176 ± 0.140
|
N.S.
| |
|
HbA1c (%)
|
5.29 ± 0.54
|
5.45 ± 0.63
|
5.85 ± 1.11
|
N.S.
| |
5.32 ± 0.60
|
5.36 ± 0.54
|
5.76 ± 0.88
|
N.S.
| |
|
TG (mg/dl)
|
104.2 ± 52.5
|
100.7 ± 51.3
|
109.4 ± 46.22
|
N.S.
| |
96.8 ± 47.0
|
115.1 ± 59.8
|
109.5 ± 41.0
|
N.S.
| |
|
HDL-C (mg/dl)
|
59.7 ± 13.7
|
61.4 ± 15.1
|
65.1 ± 17.0
|
N.S.
| |
62.1 ± 14.5
|
57.4 ± 13.2
|
59.0 ± 15.9
|
N.S.
| |
|
TG/HDL ratio
|
1.92 ± 1.20
|
1.83 ± 1.23
|
1.81 ± 0.86
|
N.S.
| |
1.73 ± 1.12
|
2.18 ± 1.33
|
1.92 ± 0.71
|
N.S.
| |
|
SBP (mmHg)
|
126 ± 14
|
126 ± 16
|
127 ± 23
|
N.S.
| |
125 ± 14
|
127 ± 15
|
132 ± 18
|
N.S.
| |
|
DBP (mmHg)
|
80 ± 10
|
77 ± 11
|
74 ± 10
|
<0.05
|
a
|
78 ± 10
|
79 ± 10
|
82 ± 11
|
N.S.
| |
|
baPWV (cm/s)
|
1402 ± 247
|
1529 ± 308
|
1758 ± 399
|
N.S.
| |
1388 ± 243
|
1515 ± 278
|
1773 ± 436
|
<0.001
|
a,b,c
|
- Data are presented as mean ± SD
-
BMI body mass index, WC waist circumference, BMD bone mineral density, HbA1c glycohemoglobin A1c, TG triglycerides, HDL-C high-density lipoprotein cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure, baPWV brachial-ankle pulse wave velocity
- *One-way ANCOVA adjusted for age and percent body fat and post hoc analysis using the least significant difference t test (mean difference between two groups): a, Normal vs. class 1; b, Normal vs. class 2; c, class 1 vs. class 2; all P < 0.05
