| |
Sarcopenia defined by ASM/Ht2
|
Sarcopenia defined by ASM/Wt
|
|---|
|
Normal
|
Class 1
|
Class 2
|
*P value
|
Normal
|
Class 1
|
Class 2
|
*P value
|
|---|
|
Sarcopenia
|
Sarcopenia
|
One-way ANCOVA
|
Post hoc analysis
|
Sarcopenia
|
Sarcopenia
|
One-way ANCOVA
|
Post hoc analysis
|
|---|
|
Number
|
656 (76.2%)
|
192 (22.3%)
|
13 (1.5%)
|
–
|
–
|
494 (57.4%)
|
306 (35.5%)
|
61 (7.1%)
|
–
|
–
|
|
Age (years)
|
60 ± 11
|
62 ± 11
|
67 ± 11
|
–
|
–
|
59 ± 11
|
62 ± 10
|
64 ± 10
|
–
|
–
|
|
Height (cm)
|
155.9 ± 5.9
|
155.3 ± 5.7
|
152.8 ± 5.8
|
N.S.
| |
156.6 ± 5.9
|
154.6 ± 5.6
|
153.7 ± 5.7
|
<0.01
|
a,b
|
|
Weight (kg)
|
53.1 ± 5.5
|
48.6 ± 5.0
|
44.4 ± 5.5
|
<0.001
|
a,b,c
|
50.8 ± 5.8
|
53.3 ± 5.5
|
55.1 ± 4.8
|
<0.001
|
a,b,c
|
|
BMI (kg/m2)
|
21.9 ± 1.8
|
20.1 ± 1.8
|
18.9 ± 1.9
|
<0.001
|
a,b,c
|
20.7 ± 1.8
|
22.3 ± 1.6
|
23.3 ± 1.3
|
N.S.
| |
|
WC (cm)
|
80.4 ± 6.9
|
77.5 ± 7.3
|
74.7 ± 7.3
|
<0.001
|
a,b,c
|
76.7 ± 6.3
|
82.7 ± 6.1
|
87.1 ± 6.5
|
N.S.
| |
|
Percent body fat (%)
|
27.5 ± 5.2
|
29.3 ± 5.0
|
30.6 ± 5.4
|
–
|
–
|
24.8 ± 4.1
|
31.4 ± 2.6
|
36.1 ± 2.4
|
–
|
–
|
|
Handgrip strength (kg)
|
25.7 ± 4.5
|
23.3 ± 3.7
|
19.7 ± 4.3
|
<0.001
|
a,b,c
|
26.1 ± 4.6
|
23.9 ± 3.8
|
22.4 ± 4.1
|
N.S.
| |
|
Whole-body BMD (g/cm2)
|
1.003 ± 0.117
|
0.956 ± 0.102
|
0.883 ± 0.112
|
<0.001
|
a,b,c
|
1.012 ± 0.119
|
0.965 ± 0.106
|
0.945 ± 0.093
|
N.S.
| |
|
Arm BMD (g/cm2)
|
0.633 ± 0.067
|
0.605 ± 0.058
|
0.561 ± 0.064
|
<0.001
|
a,b,c
|
0.640 ± 0.070
|
0.609 ± 0.057
|
0.598 ± 0.050
|
N.S.
| |
|
Lumbar spine BMD (g/cm2)
|
0.952 ± 0.174
|
0.888 ± 0.156
|
0.747 ± 0.166
|
<0.001
|
a,b,c
|
0.961 ± 0.181
|
0.902 ± 0.157
|
0.885 ± 0.144
|
N.S.
| |
|
Leg BMD (g/cm2)
|
1.026 ± 0.106
|
0.97 ± 0.095
|
0.884 ± 0.104
|
<0.001
|
a,b,c
|
1.030 ± 0.112
|
0.990 ± 0.095
|
0.968 ± 0.082
|
N.S.
| |
|
HbA1c (%)
|
5.38 ± 0.52
|
5.43 ± 0.53
|
5.36 ± 0.52
|
N.S.
| |
5.31 ± 0.41
|
5.48 ± 0.64
|
5.56 ± 0.57
|
N.S.
| |
|
TG (mg/dl)
|
82.6 ± 39.6
|
88.0 ± 46.1
|
90.2 ± 45.7
|
N.S.
| |
76.0 ± 34.6
|
90.9 ± 44.5
|
112.5 ± 54.5
|
<0.05
|
a,b,c
|
|
HDL-C (mg/dl)
|
71.3 ± 16.8
|
70.2 ± 15.3
|
72.5 ± 15.8
|
N.S.
| |
75.0 ± 16.9
|
66.8 ± 14.4
|
61.3 ± 14.3
|
N.S.
| |
|
TG/HDL ratio
|
1.29 ± 0.92
|
1.39 ± 1.05
|
1.47 ± 1.05
|
N.S.
| |
1.11 ± 0.71
|
1.52 ± 1.11
|
2.00 ± 1.32
|
<0.05
|
a,b,c
|
|
SBP (mmHg)
|
120 ± 17
|
122 ± 20
|
120 ± 19
|
N.S.
| |
118 ± 17
|
123 ± 18
|
130 ± 20
|
<0.05
|
a,b,c
|
|
DBP (mmHg)
|
71 ± 10
|
72 ± 12
|
69 ± 11
|
N.S.
| |
70 ± 10
|
72 ± 10
|
75 ± 12
|
<0.05
|
a,b,c
|
|
baPWV (cm/s)
|
1319 ± 239
|
1433 ± 313
|
1607 ± 316
|
<0.001
|
a,b,c
|
1306 ± 245
|
1386 ± 270
|
1512 ± 301
|
<0.01
|
a,b,c
|
- Data are presented as mean ± SD
-
BMI body mass index, WC waist circumference, BMD bone mineral density, HbA1c glycohemoglobin A1c, TG triglycerides, HDL-C high-density lipoprotein cholesterol, SBP systolic blood pressure, DBP diastolic blood pressure, baPWV brachial-ankle pulse wave velocity
- *One-way ANCOVA adjusted for age and percent body fat and post hoc analysis using the least significant difference t test (mean difference between two groups): a, Normal vs. class 1; b, Normal vs. class 2; c, class 1 vs. class 2; all P < 0.05
