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Table 2 Odds ratios (ORs) and 95% confidence intervals (CIs) for hypertension in relation to HDL-cholesterol stratified by circulating CD34-positive cell levels

From: Association between high-density lipoprotein-cholesterol and hypertension in relation to circulating CD34-positive cell levels

  HDL-cholesterol tertiles p for trend 1 SD increment of HDL (13.8 mg/dL)
T1 (low) T2 T3 (high)
Total subjects
 No. of participants 161 155 161   
 No. of cases (%) 101 (62.7) 98 (63.2) 99 (61.5)   
 Age-adjusted ORs 1.00 1.02 (0.64, 1.61) 0.96 (0.61, 1.51) 0.860 1.05 (0.87, 1.27)
 Age- and BMI-adjusted ORs 1.00 1.08 (0.67, 1.72) 1.22 (0.76, 1.96) 0.415 1.19 (0.97, 1.45)
 Multivariable ORs 1.00 1.06 (0.66, 1.72) 1.09 (0.66, 1.79) 0.737 1.13 (0.92, 1.40)
High CD34-positive cell (≥0.99 cells/μL)
 No. of participants 89 78 73   
 No. of cases (%) 53 (59.6) 52 (66.7) 51 (69.9)   
 Age-adjusted ORs 1.00 1.31 (0.69, 2.48) 1.63 (0.84, 3.16) 0.142 1.24 (0.95, 1.62)
 Age- and BMI-adjusted ORs 1.00 1.43 (0.75, 2.75) 2.12 (1.05, 4.27) 0.035 1.40 (1.05, 1.86)
 Multivariable ORs 1.00 1.48 (0.76, 2.88) 2.34 (1.11, 4.91) 0.025 1.44 (1.06, 1.96)
Low CD34-positive cell (<0.99 cells/μL)
 No. of participants 72 77 88   
 No. of cases (%) 48 (66.7) 46 (59.7) 48 (54.5)   
 Age-adjusted ORs 1.00 0.77 (0.39, 1.51) 0.60 (0.31, 1.15) 0.123 0.89 (0.68, 1.17)
 Age- and BMI-adjusted ORs 1.00 0.76 (0.38, 1.51) 0.72 (0.37, 1.41) 0.345 1.00 (0.75, 1.33)
 Multivariable ORs 1.00 0.69 (0.33, 1.44) 0.50 (0.24, 1.05) 0.068 0.87 (0.63, 1.19)
  1. Hypertension is defined as systolic blood pressure ≥140 mmHg, and/or diastolic blood pressure ≥90 mmHg, and/or antihypertensive medication use. Multivariable ORs: adjusted further for age and BMI, smoking status, alcohol consumption, HbA1C, LDL, AST, γ-GTP, UA and GFR. HDL tertiles are <51 mg/dL for T1, 51–61 mg/dL for T2, and >61 mg/dL for T3