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Table 1 Anthropometric and clinical characteristics of study subjects by Mt5178 C/A genotype

From: Longevity-associated mitochondrial DNA 5178 C/A polymorphism modifies effect of aging on renal function in male Japanese health checkup examinees: an exploratory cross-sectional study

 

Mt5178C, N = 247

Mt5178A, N = 157

P value

Age (years)*

54.4 (7.8)

53.2 (7.8)

0.142

Body mass index (kg/m2)*

23.3 (2.8)

23.5 (2.6)

0.366

Systolic blood pressure (mmHg)*

125.8 (15.8)

125.7 (14.1)

0.934

Diastolic blood pressure (mmHg)**

73.9 (10.6)

73.7 (9.1)

0.817

LDL cholesterol (mg/dL)*

121.3 (34.4)

118.0 (30.8)

0.319

HDL cholesterol (mg/dL)**

54.5 (13.5)

56.2 (16.1)

0.285

Triglyceride (mg/dL)*

137.4 (91.2)

139.4 (90.2)

0.826

Fasting plasma glucose (mg/dL)**

99.7 (18.9)

98.2 (11.0)

0.334

Uric acid (mg/dL)*

5.94 (1.24)

5.94 (1.22)

0.970

Blood urea nitrogen (mg/dL)*

15.8 (3.7)

15.3 (3.4)

0.157

Creatinine (mg/dL)*

0.813 (0.118)

0.798 (0.111)

0.187

Estimated glomerular filtration rate (eGFR; mL/min/1.73 m2)*

79.5 (13.6)

81.4 (12.4)

0.157

Renal function (≥ 90/75–90/60–75/< 60) (%)***

18.6/40.9/36.0/4.5

24.8/42.0/30.6/2.6

0.311

Smoking status (never- or ex-smoker/1–20 cigarettes per day/≥ 21 cigarettes per day) (%)***

59.1/29.2/11.7

59.2/25.5/15.3

0.500

Alcohol consumption (non- or ex-drinker/occasionally/daily) (%)***

18.2/35.2/46.6

13.4/38.2/48.4

0.431

Green tea consumption (≤ 1 cup per day/2–3 cups per day/4–5 cups per day/≥ 6 cups per day) (%)***

26.3/30.3/21.9/21.5

28.0/33.8/17.7/18.5

0.782

Antihypertensive medication (%)***

19.4

13.4

0.115

  1. Age, body mass index, systolic blood pressure, diastolic blood pressure, LDL cholesterol levels, HDL cholesterol levels, triglyceride levels, fasting plasma glucose levels, uric acid levels, blood urea nitrogen levels, creatinine levels, and eGFR are given as means (SD). All P values depict significant differences between Mt5178C and Mt5178A genotypic men
  2. *Student’s t test, **Welch’s t test, ***Chi-squared test