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Table 1 Anthropometric and clinical characteristics of study subjects by Mt5178 C/A genotype

From: Longevity-associated mitochondrial DNA 5178 C/A polymorphism modifies effect of aging on renal function in male Japanese health checkup examinees: an exploratory cross-sectional study

  Mt5178C, N = 247 Mt5178A, N = 157 P value
Age (years)* 54.4 (7.8) 53.2 (7.8) 0.142
Body mass index (kg/m2)* 23.3 (2.8) 23.5 (2.6) 0.366
Systolic blood pressure (mmHg)* 125.8 (15.8) 125.7 (14.1) 0.934
Diastolic blood pressure (mmHg)** 73.9 (10.6) 73.7 (9.1) 0.817
LDL cholesterol (mg/dL)* 121.3 (34.4) 118.0 (30.8) 0.319
HDL cholesterol (mg/dL)** 54.5 (13.5) 56.2 (16.1) 0.285
Triglyceride (mg/dL)* 137.4 (91.2) 139.4 (90.2) 0.826
Fasting plasma glucose (mg/dL)** 99.7 (18.9) 98.2 (11.0) 0.334
Uric acid (mg/dL)* 5.94 (1.24) 5.94 (1.22) 0.970
Blood urea nitrogen (mg/dL)* 15.8 (3.7) 15.3 (3.4) 0.157
Creatinine (mg/dL)* 0.813 (0.118) 0.798 (0.111) 0.187
Estimated glomerular filtration rate (eGFR; mL/min/1.73 m2)* 79.5 (13.6) 81.4 (12.4) 0.157
Renal function (≥ 90/75–90/60–75/< 60) (%)*** 18.6/40.9/36.0/4.5 24.8/42.0/30.6/2.6 0.311
Smoking status (never- or ex-smoker/1–20 cigarettes per day/≥ 21 cigarettes per day) (%)*** 59.1/29.2/11.7 59.2/25.5/15.3 0.500
Alcohol consumption (non- or ex-drinker/occasionally/daily) (%)*** 18.2/35.2/46.6 13.4/38.2/48.4 0.431
Green tea consumption (≤ 1 cup per day/2–3 cups per day/4–5 cups per day/≥ 6 cups per day) (%)*** 26.3/30.3/21.9/21.5 28.0/33.8/17.7/18.5 0.782
Antihypertensive medication (%)*** 19.4 13.4 0.115
  1. Age, body mass index, systolic blood pressure, diastolic blood pressure, LDL cholesterol levels, HDL cholesterol levels, triglyceride levels, fasting plasma glucose levels, uric acid levels, blood urea nitrogen levels, creatinine levels, and eGFR are given as means (SD). All P values depict significant differences between Mt5178C and Mt5178A genotypic men
  2. *Student’s t test, **Welch’s t test, ***Chi-squared test