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Table 1 Sensitivity and specificity of the in-house TPO-Ab ELISA for 182 matched plasma, venous DBS (vDBS), and fingerprick DBS (fDBS) samples

From: Development and validation of an ELISA for a biomarker of thyroid dysfunction, thyroid peroxidase autoantibodies (TPO-Ab), in dried blood spots

  True positives (TP) True negatives (TN) False negatives (FN) False positives (FP) Sensitivity (%) Specificity (%)
TP/(TP + FN) 95% CI TN/(TN+ FP) (%) 95% CI
Plasma 12 169 0 1 100 73.5–100% 99.4 96.8–100%
vDBS 12 168 0 2 100 73.5–100% 98.8 95.8–99.9%
fDBS 11 167 1 3 91.7 61.3–99.8% 98.2 94.9–99.6%
  1. Note that a cut-off of 26 IU/mL was used