Oxytocin receptor gene polymorphism (rs53576) and digit ratio associates with aggression: comparison in seven ethnic groups

Table 4 Association between aggression subscales (z-score), sex, OXTR rs53576, and right-hand 2D:4D ratio (z-score)

N	Trait	Predictors	F	P (sig.)	Partial eta²	Model R²
1	Physical aggression^Z	Sex	53.958	< 0.001	0.031	0.039
		OXTR rs53576	2.401	0.091	0.003
		R2D:4D^Z	2.312	0.129	0.001
		OXTR rs53576 * R2D:4D^Z	0.543	0.581	0.001
		Sex * OXTR rs53576	1.591	0.204	0.002
		Sex * R2D:4D	1.180	0.277	0.001
2	Verbal aggression^Z	Sex	10.991	0.001	0.006	0.014
		OXTR_rs53576	2.587	0.076	0.003
		R2D:4D^Z	0.407	0.524	< 0.001
		OXTR rs53576 * R2D:4D ^Z	2.011	0.134	0.002
		Sex * OXTR rs53576	0.151	0.859	< 0.001
		Sex * R2D:4D	0.090	0.764	< 0.001
3	Anger^Z	Sex	6.767	0.009	0.004	0.018
		OXTR rs53576	3.502	0.030	0.004
		R2D:4D^Z	7.109	0.008	0.004
		OXTR rs53576 * R2D:4D^Z	4.270	0.014	0.005
		Sex * OXTR rs53576	0.675	0.509	0.001
		Sex * R2D:4D	2.470	0.116	0.001
4	Hostility^Z	Sex	4.427	0.036	0.003	0.015
		OXTR rs53576	4.239	0.015	0.005
		R2D:4D^Z	3.900	0.048	0.002
		OXTR rs53576 * R2D:4D^Z	0.986	0.373	0.001
		Sex * OXTR rs53576	2.228	0.108	0.003
		Sex * R2D:4D	0.581	0.446	< 0.001

Four univariate general linear models (ANCOVA) with multiple predictors are presented
OXTR (rs53576): AA (N = 282), AG (N = 755), GG (N = 668); sex: male (N = 837), female (N = 868)
N model number; Trait dependent variable, one of the four subscales of BPAQ per each model; Predictors independent variables, * interactions; F test statistics; P level of statistical significance (bold: p < 0.05); partial eta² effect size; Model R² model R-squared
^ZVariable after z-score standardization

ISSN: 1880-6805