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Table 2 Association between ALDH2 genotype and grip strength and chair stand test in the ≥ 55 age groups

From: ALDH2 gene polymorphism is associated with fitness in the elderly Japanese population

 

Genotype

Dominant

Recessive

P value

GG

n = 481

GA

n = 272

AA

n = 61

AA + GA

n = 333

GA + GG

N = 753

Genotype

Dominant

Recessive

Women, n (%)

311 (65)

160 (59)

36 (59)

196 (59)

471 (63)

0.245*

0.198*

0.704*

Age, year

68.8 ± 7.9

69.4 ± 8.3

70.6 ± 8.5

69.6 ± 8.3

69.1 ± 8.1

0.217

0.143

0.091

Hight, cm

158.4 ± 8.9

159.5 ± 8.4

158.2 ± 8.4

159.2 ± 8.4

158.8 ± 8.6

0.233

0.183

0.529

Weight, kg

56.6 ± 10.4

56.2 ± 9.3

57.8 ± 9.2

56.4 ± 9.3

56.5 ± 9.9

0.543

0.865

0.356

BMI, kg•m−2

22.4 ± 2.9

22.0 ± 2.7

23.0 ± 2.9

22.2 ± 2.8

22.3 ± 2.8

0.035

0.277

0.075

Systolic blood pressure, mmHg

135.6 ± 18.6

134.6 ± 18.2

137.7 ± 20.7

135.3 ± 18.7

135.3 ± 18.5

0.491

0.854

0.280

Diastolic blood pressure

78.0 ± 11.8

77.5 ± 12.8

78.4 ± 11.2

77.7 ± 12.5

77.9 ± 11.9

0.810

0.812

0.495

Exercise habit, yes (%)

372 (77)

216 (79)

49 (80)

265 (80)

588 (78)

0.739*

0.148*

0.734*

Grip strength, kg

28.9 ± 8.5

29.3 ± 7.9

28.1 ± 9.1

29.0 ± 8.0

29.1 ± 8.3

0.138†

0.245†

0.021†

Chair stand test, times

24.8 ± 6.3

24.3 ± 6.3

23.2 ± 7.2

24.0 ± 6.4

24.6 ± 6.3

0.270†

0.089†

0.124†

  1. Mean ± SD. BMI body mass index.
  2. *Pearson’s χ2 test
  3. ANCOVA adjusted by age, sex, and exercise habit