Figure 4

Mean skin temperature. Changes in mean skin temperature (mean ± standard error) in summer D (●; n = 7), summer non-D (○; n = 8), winter D (■; n = 7), winter non-D (□; n = 8) groups. ^aP < 0.05 compared with summer D (●) and winter D (■), and ^bP < 0.05 compared with summer non-D (○) and winter non-D (□). In a post hoc test, skin temperature at rest prior to cold exposure was lower in winter than in summer in both haplotype groups, but no other significant differences were observed