Fig. 4

Time series variations of SpO₂ at 28 °C in groups of haplotypes (a) and diplotypes (b) estimated by using rs12097901 and rs2790859 genotype frequencies. Estimated diplotypes with a sample size of < 5 were removed. The ordinate axis represents SpO₂ and the abscissa axis represents time (min): 30 and 60 min are equivalent to altitudes of 2500 and 4000 m, respectively. Red characters represent highlander alleles. Line colors represent each group of haplotypes or diplotypes. Data are presented as the mean ± standard error of the mean