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Table 2 Time series variations of SpO2 in individuals with different genotypes

From: Association of EGLN1 genetic polymorphisms with SpO2 responses to acute hypobaric hypoxia in a Japanese cohort

RefSNP ID

Positiona

Genotypeb

2Nc

SpO2d

SpO2 latencye

P valuef

0 min

30 min

60 min

90 min

rs480902

1: 231,395,881

CC

14

98.3 ± 0.24

93.6 ± 0.35

86.0 ± 0.84

97.0 ± 0.30

58.1 ± 1.61

0.367

TC

26

98.5 ± 0.19

94.1 ± 0.31

86.2 ± 0.57

97.6 ± 0.29

57.2 ± 1.46

TT

6

98.2 ± 0.67

93.7 ± 0.41

85.7 ± 0.56

97.2 ± 0.63

55.0 ± 2.27

rs479200

1: 231,408,034

TT

17

98.3 ± 0.22

93.6 ± 0.30

86.2 ± 0.73

97.1 ± 0.27

57.5 ± 1.52

0.527

TC

22

98.5 ± 0.22

94.2 ± 0.36

86.1 ± 0.66

97.5 ± 0.34

57.5 ± 1.63

CC

7

98.3 ± 0.57

93.6 ± 0.38

85.8 ± 0.48

97.4 ± 0.55

55.1 ± 1.92

rs2808611

1: 231,412,734

AA

15

98.3 ± 0.25

93.7 ± 0.32

86.1 ± 0.80

97.0 ± 0.30

58.1 ± 1.52

0.766

GA

23

98.5 ± 0.21

94.0 ± 0.36

86.0 ± 0.63

97.5 ± 0.31

57.4 ± 1.55

GG

8

98.4 ± 0.50

93.9 ± 0.34

86.2 ± 0.58

97.5 ± 0.57

54.8 ± 2.25

rs12097901

1: 231,421,509

GG

14

99.0 ± 0.10

94.5 ± 0.31

87.2 ± 0.60

97.2 ± 0.33

61.2 ± 1.35

0.006

CG

21

98.2 ± 0.20

93.4 ± 0.32

85.5 ± 0.68

97.3 ± 0.30

56.1 ± 1.56

CC

11

98.1 ± 0.46

93.9 ± 0.47

85.8 ± 0.79

97.6 ± 0.51

54.1 ± 1.76

rs2790859

1: 231,465,611

TT

16

98.0 ± 0.33

93.5 ± 0.35

85.4 ± 0.71

97.3 ± 0.35

55.2 ± 1.44

0.014

TC

25

98.5 ± 0.17

94.0 ± 0.30

86.1 ± 0.56

97.5 ± 0.28

56.9 ± 1.38

CC

5

99.1 ± 0.19

94.6 ± 0.55

88.2 ± 0.77

96.6 ± 0.61

64.8 ± 1.71

  1. Abbreviation: SpO 2 percutaneous arterial oxygen saturation
  2. aPosition in NCBI build GRCh38
  3. bHighlander alleles are shown in italics (see Table 1)
  4. cThe number of chromosomes
  5. dQuantitative data are presented as the mean ± standard error of the mean
  6. eLatency in the first reading and time to stabilization of SpO2
  7. fP values estimated by the GLM analysis for SpO2 latency