Table 4 Haplotype analysis for 12 SNPs of the NR3C1 gene in HAPE and control groups
From: NR3C1 gene polymorphisms are associated with high-altitude pulmonary edema in Han Chinese
Haplotype | HAPE-p (freq) | HAPE-r (freq) | χ 2 | P value | Odds ratio [95%CI] |
|---|---|---|---|---|---|
AAAAAATGGCCA | 11.47 (0.043) | 21.87 (0.081) | 3.502 | 0.0613 | 0.500 [0.239~1.046] |
AACACTCAAGTG | 206.53 (0.776) | 174.13 (0.645) | 11.206 | 0.0008 | 2.044 [1.339~3.120] |
GGAGCACGACCG | 24.00 (0.090) | 39.00 (0.144) | 4.127 | 0.0422 | 0.573 [0.333~0.985] |
GGCGCTCAAGTG | 8.47 (0.032) | 14.87 (0.055) | 1.857 | 0.1729 | 0.553 [0.233~1.311] |