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Table 3 Odds ratios (ORs) and 95% confidence intervals (CIs) of proteinuria in relation to thyroid-stimulating hormone (TSH) by thyroid cyst

From: Association between thyroid-stimulating hormone (TSH) and proteinuria in relation to thyroid cyst in a euthyroid general population

  TSH levels p Log TSH p (goodness of fit test)
(Low) (Medium) (High)
Total   
 No. of participants 526 539 530  
 No. of proteinuria cases (%) 25 (4.8) 30 (5.6) 31 (5.8)
 Model 1 Ref 1.21 (0.70, 2.08) 1.32 (0.76, 2.27) 0.325 1.13 (0.70, 1.81) 0.933
 Model 2 Ref 1.19 (0.68, 2.07) 1.35 (0.77, 2.36) 0.296 1.14 (0.70, 1.86) 0.370
Thyroid cyst (−)   
 No. of participants 344 374 352  
 No. of proteinuria cases (%) 9 (2.6) 22 (5.9) 25 (7.1)
 Model 1 Ref 2.39 (1.08, 5.26) 3.06 (1.40, 6.69) 0.005 2.10 (1.13, 3.90) 0.135
 Model 2 Ref 2.38 (1.07, 5.30) 3.08 (1.38, 6.86) 0.006 2.06 (1.09, 3.90) 0.647
Thyroid cyst (+)   
 No. of participants 182 165 178  
 No. of proteinuria cases (%) 16 (8.8) 8 (4.8) 6 (3.4)
 Model 1 Ref 0.55 (0.23, 1.34) 0.37 (0.14, 0.98) 0.037 0.41 (0.18, 0.89) 0.842
 Model 2 Ref 0.54 (0.21, 1.38) 0.34 (0.12, 0.94) 0.031 0.40 (0.18, 0.89) 0.849
  1. Ref reference. Model 1: adjusted for sex and age. Model 2: + BMI, smoking status (never, former, current), drinking status (none, often, daily), systolic blood pressure (SBP), triglycerides (TG), high-density lipoprotein cholesterol (HDLc), and hemoglobin A1c (HbA1c). Tertile values of TSH for men and women are < 1.19 μIU/mL and < 1.24 μIU/mL for (low), 1.19‑1.82 μIU/mL and 1.24‑1.96 μIU/mL for (medium), and 1.83 μIU/mL ≤ and 1.97 μIU/mL ≤ for (high)