The effect of FTO gene rs9939609 polymorphism on the association between colorectal cancer and different types of dietary fat intake: a case-control study

Table 5 Logistic regression of the association between colorectal cancer and dietary intake among people with AA/AT FTO rs9939609 genotype

	Model 1		Model 2		Model 3		Model 4
	OR (CI95%)	P	OR (CI95%)	P	OR (CI95%)	P	OR (CI95%)	P
Total fat	0.99 (0.95–1.02)	0.552	0.98 (0.95–1.02)	0.551	0.98 (0.95–1.02)	0.552	1.01 (0.96–1.06)	0.522
Cholesterol	1.01 (1.00–1.02)	0.014	1.01 (1.00–1.02)	0.041	1.01 (1.00–1.02	0.043	1.01 (1.00–1.02)	0.037
SFA	0.95 (0.90–1.01)	0.131	0.96 (0.91–1.03)	0.304	0.96 (0.91–1.03)	0.303	0.99 (0.92–1.07)	0.938
MUFAs	1.00 (0.93–1.07)	0.957	1.01 (0.93–1.09)	0.752	1.01 (0.93–1.09)	0.751	1.04 (0.96–1.14)	0.282
PUFAs	0.90 (0.82–1.00)	0.051	0.90 (0.82–1.00)	0.052	0.90 (0.82–1.00)	0.054	0.92 (0.83–1.02)	0.112
Oleic acid	1.12 (1.03–1.21)	0.008	1.11 (1.02–1.25)	0.012	1.11 (1.02–1.25)	0.011	1.08 (0.98–1.19)	0.091
Linoleic acid	1.11 (0.98–1.21)	0.049	1.13 (0.98–1.25)	0.048	1.13 2(0.98–1.25)	0.06	1.11 (0.99–1.23)	0.052
α-Linolenic acid	1.11 (0.74–1.65)	0.612	1.12 (0.71–1.77)	0.601	1.12 (0.71–1.77)	0.603	1.22 (0.76–1.94)	0.411
EPA	1.01 (0.01–5.43)	0.087	1.01 (0.01–5.54)	0.091	1.01 (0.01–5.63)	0.092	1.01 (0.01–5.78)	0.153
DHA	6.97 (0.6–13.27)	0.424	2.02 (0.12–6.62)	0.221	2.02 (0.12–6.62)	0.218	3.10 (13–4.61)	0.211

Model 1: crude. Model 2: adjusted for age and sex. Model 3: adjusted for age, sex, physical activity, alcohol use, and smoking. Model 4: adjusted for age, sex, physical activity, alcohol use, smoking, calorie intake, and BMI
SFA Saturated fatty acids, EPA, Eicosapentaenoic acid, DHA Docosahexaenoic acid, MUFAs Monounsaturated fatty acids, PUFAs Polyunsaturated fatty acids

ISSN: 1880-6805