FTO and MC4R polymorphisms, and selected pre-, peri- and postnatal factors as determinants of body mass index and fatness in children: a thorough analysis of the associations

Table 13 Multiple forward regression results predicting BMI z scores, FMI z scores, FFMI z scores and FatM z scores in boys

Variable	R2	β	F	P-value
Model 1: BMI z scores	0.146		4.15	< 0.001
Paternal BMI		0.08		0.002
Mother's age at the child’s birth		-0.04		0.03
Maternal BMI before pregnancy		0.07		0.02
Prenatal stress (ref. 0)		0.34		0.09
Eating behaviours (ref. good)		0.28		0.12
Maternal educational level (ref. higher)		0.26		0.19
MC4R (ref. TT)		0.21		0.27
Model 2: FMI z scores	0.080		5.04	< 0.002
Maternal educational level (ref. higher)		0.17		0.02
Mother's age at the child’s birth		-0.15		0.04
Paternal BMI		0.15		0.046
Model 3: FFMI z scores	0.165		5.69	< 0.001
Paternal BMI		0.24		0.001
Eating behaviours (ref. good)		0.16		0.02
Maternal current BMI		0.17		0.02
Mother's age at the child’s birth		-0.14		0.05
Prenatal stress (ref. 0)		0.10		0.14
Paternal educational level (ref. higher)		0.08		0.27
Model 4: FatM z scores	0.085		4.08	< 0.001
Maternal educational level (ref. higher)		0.16		0.04
Paternal BMI		0.15		0.04
Mother's age at the child’s birth		-0.16		0.03
Highest body weight in pregnancy		0.08		0.30

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