Table 14 Interactions between ACEs and polymorphisms of FTO and MC4R genes

BMI z scores

 ACE 0,1,2,3 + 

2.59

0.02

1.80

0.10

 Life threatened

2.20

0.11

0.10

0.90

 Life threatened witness

1.73

0.17

0.30

0.74

 Violence victim

0.58

0.56

0.16

0.85

 Violence witness

0.50

0.61

0.22

0.80

 Death of someone close

1.65

0.19

0.10

0.91

 Family conflicts

1.94

0.15

0.02

0.98

 Separation from parent

3.06

0.048

3.07

0.03

 School problems

5.73

0.004

1.33

0.27

 Other unspecified stressors

4.60

0.01

0.14

0.87

 ACE at least one

0.58

0.55

0.06

0.94

FMI z scores

 ACE 0,1,2,3 + 

1.65

0.13

2.31

0.03

 Life threatened

1.32

0.26

0.08

0.92

 Life threatened witness

1.96

0.14

0.73

0.48

 Violence victim

0.44

0.65

0.11

0.90

 Violence witness

0.27

0.76

0.07

0.93

 Death of someone close

0.15

0.86

0.55

0.58

 Family conflicts

1.55

0.21

0.55

0.58

 Separation from parent

0.93

0.40

8.34

 < 0.001

 School problems

4.09

0.02

0.81

0.44

 Other unspecified stressors

3.13

0.04

1.02

0.36

 ACE at least one

0.63

0.53

0.26

0.77

FFMI z scores

 ACE 0,1,2,3 + 

1.70

0.12

1.65

0.13

 Life threatened

2.67

0.07

0.18

0.84

 Life threatened witness

0.50

0.61

0.39

0.67

 Violence victim

1.19

0.30

0.69

0.50

 Violence witness

0.01

0.99

0.74

0.48

 Death of someone close

2.33

0.10

0.60

0.55

 Family conflicts

2.07

0.13

0.68

0.51

 Separation from parent

3.27

0.04

2.16

0.11

 School problems

4.95

0.007

1.91

0.15

 Other unspecified stressors

3.03

0.04

0.54

0.58

 ACE at least one

0.66

0.52

1.27

0.28

FatM z scores

 ACE 0,1,2,3 + 

0.80

0.57

2.27

0.04

 Life threatened

0.98

0.38

0.13

0.88

 Life threatened witness

0.62

0.54

0.27

0.77

 Violence victim

0.41

0.67

0.007

0.99

 Violence witness

0.22

0.81

0.13

0.88

 Death of someone close

0.31

0.74

0.13

0.88

 Family conflicts

1.34

0.26

0.11

0.90

 Separation from parent

0.75

0.47

9.73

 < 0.001

 School problems

2.28

0.10

0.34

0.71

 Other unspecified stressors

1.99

0.14

0.22

0.80

 ACE at least one

0.64

0.53

0.07

0.93